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Chemical reprogramming of Caenorhabditis elegans germ cell fate

Small-molecules can control cell fate in vivo and may allow directed induction of desired cell types, providing an attractive alternative to transplant-based approaches in regenerative medicine. We have chemically induced functional oocytes in C. elegans adults that otherwise produced only sperm. Th...

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Detalhes bibliográficos
Main Authors: Morgan, Clinton T., Lee, Myon-Hee, Kimble, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808631/
https://ncbi.nlm.nih.gov/pubmed/20081824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.282
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