Passively Administered Pooled Human Immunoglobulins Exert IL-10 Dependent Anti-Inflammatory Effects that Protect against Fatal HSV Encephalitis

HSV-1 is the leading cause of sporadic encephalitis in humans. HSV infection of susceptible 129S6 mice results in fatal encephalitis (HSE) caused by massive inflammatory brainstem lesions comprising monocytes and neutrophils. During infection with pathogenic microorganisms or autoimmune disease, IgG...

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Main Authors: Ramakrishna, Chandran, Newo, Alain N. S., Shen, Yueh-Wei, Cantin, Edouard
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107211/
https://ncbi.nlm.nih.gov/pubmed/21655109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002071
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