Passively Administered Pooled Human Immunoglobulins Exert IL-10 Dependent Anti-Inflammatory Effects that Protect against Fatal HSV Encephalitis

HSV-1 is the leading cause of sporadic encephalitis in humans. HSV infection of susceptible 129S6 mice results in fatal encephalitis (HSE) caused by massive inflammatory brainstem lesions comprising monocytes and neutrophils. During infection with pathogenic microorganisms or autoimmune disease, IgG...

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Autori principali: Ramakrishna, Chandran, Newo, Alain N. S., Shen, Yueh-Wei, Cantin, Edouard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107211/
https://ncbi.nlm.nih.gov/pubmed/21655109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002071
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