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Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

MicroRNAs (miRNAs) are small, noncoding RNAs that play a critical role in developmental and physiological processes and are implicated in the pathogenesis of several human diseases, including cancer. They function by regulating target gene expression post-transcriptionally. In this study, we examine...

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Autors principals: Gaur, Arti B., Holbeck, Susan L., Colburn, Nancy H., Israel, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107097/
https://ncbi.nlm.nih.gov/pubmed/21636706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor033
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