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A Streamlined Mutation Detection System: Multicolor Post-PCR Fluorescence Labeling and Single-Strand Conformational Polymorphism Analysis by Capillary Electrophoresis

Effective use of knowledge of human genome sequences in studies of hereditary diseases or cancer heavily depends on efficient methods for detection of mutations in individual samples. We describe here a simple and efficient mutation scanning system in which PCR products are post-labeled with two dif...

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Autors principals: Inazuka, Masakazu, Wenz, Hans-Michael, Sakabe, Munechika, Tahira, Tomoko, Hayashi, Kenshi
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC310684/
https://ncbi.nlm.nih.gov/pubmed/9371745
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