Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.
We developed mobility shift analysis of single-stranded DNAs on neutral polyacrylamide gel electrophoresis to detect DNA polymorphisms. This method follows digestion of genomic DNA with restriction endonucleases, denaturation in alkaline solution, and electrophoresis on a neutral polyacrylamide gel....
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286999/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2565038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.8.2766 |
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