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Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms.

We developed mobility shift analysis of single-stranded DNAs on neutral polyacrylamide gel electrophoresis to detect DNA polymorphisms. This method follows digestion of genomic DNA with restriction endonucleases, denaturation in alkaline solution, and electrophoresis on a neutral polyacrylamide gel....

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Autors principals: Orita, M, Iwahana, H, Kanazawa, H, Hayashi, K, Sekiya, T
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC286999/
https://ncbi.nlm.nih.gov/pubmed/2565038
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