Complications of Tumor Necrosis Factor-± Blockade in Chronic Granulomatous Disease—Related Colitis

Background. Chronic granulomatous disease (CGD) is a genetic disorder of the phagocyte NADPH oxidase, which predisposes patients to infections and inflammatory complications, including severe colitis. Management of CGD colitis is a challenge because standard immunosuppressive therapy increases the r...

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Bibliographic Details
Main Authors: Uzel, Gulbu, Orange, Jordan S., Poliak, Nina, Marciano, Beatriz E., Heller, Theo, Holland, Steven M.
Format: Artigo
Language:Inglês
Published: The University of Chicago Press 2010
Subjects:
Articles and Commentaries
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106244/
https://ncbi.nlm.nih.gov/pubmed/21058909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/657308
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