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Treating brain tumors with PDE4 Inhibitors

Speculation regarding dysregulation of cyclic adenosine monophosphate (cAMP) metabolism in oncogenesis has existed since the discovery of cAMP more than 50 years ago. Recent data confirms the relevance of disordered cAMP metabolism to the genesis of multiple cancers and suggests that the mechanism m...

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Detalhes bibliográficos
Main Authors: Sengupta, Rajarshi, Sun, Tao, Warrington, Nicole M, Rubin, Joshua B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106141/
https://ncbi.nlm.nih.gov/pubmed/21450351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2011.02.015
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