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The retinoblastoma protein binds E2F residues required for activation in vivo and TBP binding in vitro.

The retinoblastoma (RB) tumour suppressor protein is capable of repressing the activity of promoters containing DNA binding sites for the transcription factor E2F. Recently a protein which binds RB and possesses the DNA binding characteristics of E2F has been cloned. Here we show that the E2F activa...

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Hlavní autoři: Hagemeier, C, Cook, A, Kouzarides, T
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310609/
https://ncbi.nlm.nih.gov/pubmed/8255752
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