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The heat-shock DnaK protein is required for plasmid R1 replication and it is dispensable for plasmid ColE1 replication.

Plasmid R1 replication in vitro is inactive in extracts prepared from a dnaK756 strain but is restored to normal levels upon addition of purified DnaK protein. Replication of R1 in extracts of a dnaKwt strain can be specifically inhibited with polyclonal antibodies against DnaK. RepA-dependent repli...

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Détails bibliographiques
Auteurs principaux: Giraldo-Suárez, R, Fernández-Tresguerres, E, Díaz-Orejas, R, Malki, A, Kohiyama, M
Format: Artigo
Langue:Inglês
Publié: 1993
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC310592/
https://ncbi.nlm.nih.gov/pubmed/8265367
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