Coevolution of Prostate Cancer and Bone Stroma in Three-Dimensional Coculture: Implications for Cancer Growth and Metastasis

Human bone stromal cells, after three-dimensional coculture with human prostate cancer (PCa) cells in vitro, underwent permanent cytogenetic and gene expression changes with reactive oxygen species serving as mediators. The evolved stromal cells are highly inductive of human PCa growth in mice, and...

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Autores principales: Sung, Shian-Ying, Hsieh, Chia-Ling, Law, Andrew, Zhau, Haiyen E., Pathak, Sen, Multani, Asha S., Lim, Sharon, Coleman, Ilsa M., Wu, Li-Chin, Figg, William D., Dahut, William L., Nelson, Peter, Lee, Jae K., Amin, Mahul B., Lyles, Robert, Johnstone, Peter A.J., Marshall, Fray F., Chung, Leland W.K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105756/
https://ncbi.nlm.nih.gov/pubmed/19047182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2492
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