Enzymic removal of 5-methylcytosine from DNA by a human DNA-glycosylase.
DNA 5-methylcytosine is a major factor in the silencing of mammalian genes; it is involved in gene expression, differentiation, embryogenesis and neoplastic transformation. A decrease in DNA 5-methylcytosine content is associated with activation of specific genes. There is much evidence indicating t...
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| Gepubliceerd in: | Nucleic Acids Res |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
1993
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| Online toegang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8265344/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.23.5323 |
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