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Up-regulation of homeodomain genes, DLX1 and DLX2, by FLT3 signaling
BACKGROUND: Activating mutations in fms-like tyrosine kinase-3 (FLT3) are frequent in acute myeloid leukemia and represent both a poor prognostic feature and a therapeutic target. We have identified a previously unrecognized downstream effect of FLT3 activation, namely up-regulation of the homeodoma...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105643/ https://ncbi.nlm.nih.gov/pubmed/21357706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.031179 |
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