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Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3

Molecular effects of obesity, a well-established risk factor for breast cancer progression, are mediated by adipocytokine leptin. Given the important role of leptin in breast cancer growth and metastasis, novel strategies to antagonize biological effects of this adipocytokine are much desired. We sh...

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Autori principali: Kim, Su-Hyeong, Nagalingam, Arumugam, Saxena, Neeraj K., Singh, Shivendra V., Sharma, Dipali
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105585/
https://ncbi.nlm.nih.gov/pubmed/21163886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgq267
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