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Disturbed flow: p53 SUMOylation in the turnover of endothelial cells
Disturbed blood flow induces apoptosis of vascular endothelial cells, which causes atherosclerosis. In this issue, Heo et al. (2011. J. Cell Biol. doi:10.1083/jcb.201010051) sheds light on p53’s role in this phenomenon. Disturbed flow induces peroxynitrite production, which activates protein kinase...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105545/ https://ncbi.nlm.nih.gov/pubmed/21624951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201104140 |
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