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Disconnecting the Golgi ribbon from the centrosome prevents directional cell migration and ciliogenesis
Mammalian cells exhibit a frequent pericentrosomal Golgi ribbon organization. In this paper, we show that two AKAP450 N-terminal fragments, both containing the Golgi-binding GM130-interacting domain of AKAP450, dissociated endogenous AKAP450 from the Golgi and inhibited microtubule (MT) nucleation a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105543/ https://ncbi.nlm.nih.gov/pubmed/21606206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201011014 |
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