Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis

WASP and SCAR homologue (WASH) is a recently identified and evolutionarily conserved regulator of actin polymerization. In this paper, we show that WASH coats mature Dictyostelium discoideum lysosomes and is essential for exocytosis of indigestible material. A related process, the expulsion of the l...

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Detalhes bibliográficos
Main Authors: Carnell, Michael, Zech, Tobias, Calaminus, Simon D., Ura, Seiji, Hagedorn, Monica, Johnston, Simon A., May, Robin C., Soldati, Thierry, Machesky, Laura M., Insall, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105540/
https://ncbi.nlm.nih.gov/pubmed/21606208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009119
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