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Asymmetric HIV-1 co-receptor use and replication in CD4(+) T lymphocytes

Susceptibility to infection by the human immunodeficiency virus type-1 (HIV-1), both in vitro and in vivo, requires the interaction between its envelope (Env) glycoprotein gp120 Env and the primary receptor (R), CD4, and Co-R, either CCR5 or CXCR4, members of the chemokine receptor family. CCR5-depe...

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Bibliographic Details
Main Authors: Mariani, Samanta A, Vicenzi, Elisa, Poli, Guido
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105508/
https://ncbi.nlm.nih.gov/pubmed/21284907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-S1-S8
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