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R5X4 HIV-1 coreceptor use in primary target cells: implications for coreceptor entry blocking strategies

Entry coreceptor use by HIV-1 plays a pivotal role in viral transmission, pathogenesis and disease progression. In many HIV-1 infected individuals, there is an expansion in coreceptor use from CCR5 to include CXCR4, which is associated with accelerated disease progression. While targeting HIV-1 enve...

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Detaylı Bibliyografya
Asıl Yazarlar: Loftin, Lamorris M, Kienzle, Martha, Yi, Yanjie, Collman, Ronald G
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105503/
https://ncbi.nlm.nih.gov/pubmed/21284902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-9-S1-S3
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