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Evaluation of some properties of a phosphorodithioate oligodeoxyribonucleotide for antisense application.

An all phosphorodithioate oligodeoxyribonucleotide (PS2; 17-mer) complementary to the coding region of the rabbit beta-globin mRNA was compared with the normal (PO2) and phosphorothioate (POS) oligonucleotide of the same size and sequence with respect to physicochemical properties and antisense acti...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Ghosh, M K, Ghosh, K, Dahl, O, Cohen, J S
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1993
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310546/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8284226/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.24.5761
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