Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor

Activation of the epidermal growth factor receptor (EGFR) not only initiates multiple signal-transduction pathways, including the MAP kinase (MAPK) pathway, but also triggers trafficking events that relocalize receptors from the cell surface to intracellular endocytic compartments. In this paper, we...

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Detalhes bibliográficos
Main Authors: Hanafusa, Hiroshi, Ishikawa, Kouki, Kedashiro, Shin, Saigo, Tsukasa, Iemura, Shun-ichiro, Natsume, Tohru, Komada, Masayuki, Shibuya, Hiroshi, Nara, Atsuki, Matsumoto, Kunihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105304/
https://ncbi.nlm.nih.gov/pubmed/21245839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1161
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