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The binding of an antisense oligonucleotide to a hairpin structure via triplex formation inhibits chemical and biological reactions.
We have investigated the binding of a 26-mer antisense oligodeoxynucleotide to a 69-mer DNA hairpin with a 13 base pair stem, bearing an Rsa1 restriction site. The 5' part of the 26-mer annealed to a stretch of six purines at the bottom of the hairpin. The 3' part was designed to fold back...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1993
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310525/ https://ncbi.nlm.nih.gov/pubmed/8284206 |
| Tagit: |
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