Insulin Protects against Hepatic Damage Postburn

Burn injury causes hepatic dysfunction associated with endoplasmic reticulum (ER) stress and induction of the unfolded protein response (UPR). ER stress/UPR leads to hepatic apoptosis and activation of the Jun-N-terminal kinase (JNK) signaling pathway, leading to vast metabolic alterations. Insulin...

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Detalhes bibliográficos
Main Authors: Jeschke, Marc G, Kraft, Robert, Song, Juquan, Gauglitz, Gerd G, Cox, Robert A, Brooks, Natasha C, Finnerty, Celeste C, Kulp, Gabriela A, Herndon, David N, Boehning, Darren
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105152/
https://ncbi.nlm.nih.gov/pubmed/21267509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2010.00166
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