Propranolol Improves Impaired Hepatic Phosphatidylinositol 3-Kinase/Akt Signaling after Burn Injury

Severe burn injury is associated with induction of the hepatic endoplasmic reticulum (ER) stress response. ER stress leads to activation of c-Jun N-terminal kinase (JNK), suppression of insulin receptor signaling via phosphorylation of insulin receptor substrate 1 and subsequent insulin resistance....

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Main Authors: Brooks, Natasha C, Song, Juquan, Boehning, Darren, Kraft, Robert, Finnerty, Celeste C, Herndon, David N, Jeschke, Marc G
Format: Artigo
Jezik:Inglês
Izdano: ScholarOne 2012
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388140/
https://ncbi.nlm.nih.gov/pubmed/22396018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00277
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