Histone Deacetylase (HDAC) Inhibition as a Novel Treatment for Diabetes Mellitus

Both common forms of diabetes have an inflammatory pathogenesis in which immune and metabolic factors converge on interleukin-1β as a key mediator of insulin resistance and β-cell failure. In addition to improving insulin resistance and preventing β-cell inflammatory damage, there is evidence of gen...

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Hlavní autoři: Christensen, Dan P, Dahllöf, Mattias, Lundh, Morten, Rasmussen, Daniel N, Nielsen, Mette D, Billestrup, Nils, Grunnet, Lars G, Mandrup-Poulsen, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105132/
https://ncbi.nlm.nih.gov/pubmed/21274504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00021
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