Genetic Variants of ABCC10, a Novel Tenofovir Transporter, Are Associated With Kidney Tubular Dysfunction

Background. Tenofovir (TFV) causes kidney tubular dysfunction (KTD) in some patients, but the mechanism is poorly understood. Genetic variants in TFV transporters are implicated; we explored whether ABCC10 transports TFV and whether ABCC10 single-nucleotide polymorphisms (SNPs) are associated with K...

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Hlavní autoři: Pushpakom, Sudeep P., Liptrott, Neill J., Rodríguez-Nóvoa, Sonia, Labarga, Pablo, Soriano, Vincent, Albalater, Marta, Hopper-Borge, Elizabeth, Bonora, Stefano, Di Perri, Giovanni, Back, David J., Khoo, Saye, Pirmohamed, Munir, Owen, Andrew
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
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Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105036/
https://ncbi.nlm.nih.gov/pubmed/21628669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir215
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