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Inflammation Triggers Emergency Granulopoiesis through a Density-Dependent Feedback Mechanism
Normally, neutrophil pools are maintained by homeostatic mechanisms that require the transcription factor C/EBPα. Inflammation, however, induces neutrophilia through a distinct pathway of “emergency” granulopoiesis that is dependent on C/EBPβ. Here, we show in mice that alum triggers emergency granu...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104996/ https://ncbi.nlm.nih.gov/pubmed/21655273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019957 |
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