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Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast
The Saccharomyces cerevisiae High-Osmolarity Glycerol (HOG) pathway is a conserved mitogen-activated protein kinase (MAPK) signal transduction system that often serves as a model to analyze systems level properties of MAPK signaling. Hog1, the MAPK of the HOG-pathway, can be activated by various env...
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Главные авторы: | , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Public Library of Science
2011
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Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104989/ https://ncbi.nlm.nih.gov/pubmed/21655328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020012 |
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