Design, Synthesis, and Characterization of a Highly Effective Hog1 Inhibitor: A Powerful Tool for Analyzing MAP Kinase Signaling in Yeast

The Saccharomyces cerevisiae High-Osmolarity Glycerol (HOG) pathway is a conserved mitogen-activated protein kinase (MAPK) signal transduction system that often serves as a model to analyze systems level properties of MAPK signaling. Hog1, the MAPK of the HOG-pathway, can be activated by various env...

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Detalhes bibliográficos
Main Authors: Dinér, Peter, Veide Vilg, Jenny, Kjellén, Jimmy, Migdal, Iwona, Andersson, Terese, Gebbia, Marinella, Giaever, Guri, Nislow, Corey, Hohmann, Stefan, Wysocki, Robert, Tamás, Markus J., Grøtli, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104989/
https://ncbi.nlm.nih.gov/pubmed/21655328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020012
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