Agonist Activation of F-Actin-Mediated Eosinophil Shape Change and Mediator Release Is Dependent on Rac2

BACKGROUND: Tissue recruitment and activation of eosinophils contribute to allergic symptoms by causing airway hyperresponsiveness and inflammation. Shape changes and mediator release in eosinophils may be regulated by mammalian Rho-related guanosine triphosphatases. Of these, Rac2 is essential for...

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Main Authors: Lacy, Paige, Willetts, Lian, Kim, John D., Lo, Andrea N., Lam, Bon, MacLean, Emily I., Moqbel, Redwan, Rothenberg, Marc E., Zimmermann, Nives
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2011
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104871/
https://ncbi.nlm.nih.gov/pubmed/21576984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000322597
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