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The Ca(2+)/Mg(2+) Sites of Troponin C Modulate Crossbridge-Mediated Thin Filament Activation in Cardiac Myofibrils
The Ca(2+)/Mg(2+) sites (III and IV) located in the C-terminal domain of cardiac troponin C (cTnC) have been generally considered to play a purely structural role in keeping the cTnC bound to the thin filament. However, several lines of evidence, including the discovery of cardiomyopathy-associated...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104847/ https://ncbi.nlm.nih.gov/pubmed/21539814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.04.092 |
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