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THE GREEN TEA POLYPHENOL (−)-EPIGALLOCATECHIN-3-GALLATE INHIBITS MAGNESIUM BINDING TO THE C-DOMAIN OF CARDIAC TROPONIN C
Cardiac muscle contraction is activated via the single Ca(2+)-binding site (site II) in the N-domain of troponin C (cTnC). The two Ca(2+)/Mg(2+) binding sites in the C-domain of cTnC (sites III and IV) have been considered to play a purely structural role in anchoring cTnC to the thin filament. Howe...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3637861/ https://ncbi.nlm.nih.gov/pubmed/23417789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-013-9338-9 |
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