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Preparation of trimers and tetramers of mixed sequence oligodeoxynucleoside methylphosphonates and assignment of configurations at the chiral phosphorus.

Synthesis of stereoregular DNA methylphosphonates has been accomplished for homo-oligomers, but remains a formidable problem for oligomers of a defined antisense target sequence. In this work, four trimer and tetramer deoxynucleoside methylphosphonates of mixed sequence (dACA, dCCAA, dAGGG, and dGCA...

詳細記述

保存先:
書誌詳細
主要な著者: Vyazovkina, E V, Rife, J P, Lebedev, A V, Wickstrom, E
フォーマット: Artigo
言語:Inglês
出版事項: 1993
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC310481/
https://ncbi.nlm.nih.gov/pubmed/8290358
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