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Angiopoietin-1 is essential in mouse vasculature during development and in response to injury

Angiopoietin-1/Tek signaling is a critical regulator of blood vessel development, with conventional knockout of angiopoietin-1 or Tek in mice being embryonically lethal due to vascular defects. In addition, angiopoietin-1 is thought to be required for the stability of mature vessels. Using a Cre-Lox...

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Detalhes bibliográficos
Main Authors: Jeansson, Marie, Gawlik, Alexander, Anderson, Gregory, Li, Chengjin, Kerjaschki, Dontscho, Henkelman, Mark, Quaggin, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104773/
https://ncbi.nlm.nih.gov/pubmed/21606590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46322
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