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Angiopoietin-1 is essential in mouse vasculature during development and in response to injury
Angiopoietin-1/Tek signaling is a critical regulator of blood vessel development, with conventional knockout of angiopoietin-1 or Tek in mice being embryonically lethal due to vascular defects. In addition, angiopoietin-1 is thought to be required for the stability of mature vessels. Using a Cre-Lox...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104773/ https://ncbi.nlm.nih.gov/pubmed/21606590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46322 |
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