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Exhaustion of tumor-specific CD8(+) T cells in metastases from melanoma patients
In chronic viral infections, CD8(+) T cells become functionally deficient and display multiple molecular alterations. In contrast, only little is known of self- and tumor-specific CD8(+) T cells from mice and humans. Here we determined molecular profiles of tumor-specific CD8(+) T cells from melanom...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104769/ https://ncbi.nlm.nih.gov/pubmed/21555851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI46102 |
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