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Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

High levels of HIV-1 replication during the chronic phase of infection usually correlate with rapid progression to severe immunodeficiency. However, a minority of highly viremic individuals remains asymptomatic and maintains high CD4(+) T cell counts. This tolerant profile is poorly understood and r...

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Main Authors: Rotger, Margalida, Dalmau, Judith, Rauch, Andri, McLaren, Paul, Bosinger, Steven E., Martinez, Raquel, Sandler, Netanya G., Roque, Annelys, Liebner, Julia, Battegay, Manuel, Bernasconi, Enos, Descombes, Patrick, Erkizia, Itziar, Fellay, Jacques, Hirschel, Bernard, Miró, Jose M., Palou, Eduard, Hoffmann, Matthias, Massanella, Marta, Blanco, Julià, Woods, Matthew, Günthard, Huldrych F., de Bakker, Paul, Douek, Daniel C., Silvestri, Guido, Martinez-Picado, Javier, Telenti, Amalio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104754/
https://ncbi.nlm.nih.gov/pubmed/21555857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45235
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