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Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

High levels of HIV-1 replication during the chronic phase of infection usually correlate with rapid progression to severe immunodeficiency. However, a minority of highly viremic individuals remains asymptomatic and maintains high CD4(+) T cell counts. This tolerant profile is poorly understood and r...

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Bibliografski detalji
Glavni autori: Rotger, Margalida, Dalmau, Judith, Rauch, Andri, McLaren, Paul, Bosinger, Steven E., Martinez, Raquel, Sandler, Netanya G., Roque, Annelys, Liebner, Julia, Battegay, Manuel, Bernasconi, Enos, Descombes, Patrick, Erkizia, Itziar, Fellay, Jacques, Hirschel, Bernard, Miró, Jose M., Palou, Eduard, Hoffmann, Matthias, Massanella, Marta, Blanco, Julià, Woods, Matthew, Günthard, Huldrych F., de Bakker, Paul, Douek, Daniel C., Silvestri, Guido, Martinez-Picado, Javier, Telenti, Amalio
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104754/
https://ncbi.nlm.nih.gov/pubmed/21555857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45235
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