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Generating mouse models of degenerative diseases using Cre/lox-mediated in vivo mosaic cell ablation
Most degenerative diseases begin with a gradual loss of specific cell types before reaching a threshold for symptomatic onset. However, the endogenous regenerative capacities of different tissues are difficult to study, because of the limitations of models for early stages of cell loss. Therefore, w...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104751/ https://ncbi.nlm.nih.gov/pubmed/21576819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45081 |
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