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Understanding the fate of the oxyallyl cation following Nazarov electrocyclization: sequential Wagner-Meerwein migrations and the synthesis of spirocyclic cyclopentenones

A general reaction sequence is described that involves Nazarov cyclization followed by two sequential Wagner Meerwein migrations, to afford spirocyclic compounds from divinyl ketones in the presence of one equivalent of copper(II) complexes. A detailed investigation of this sequence is described inc...

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Detalhes bibliográficos
Main Authors: Huang, Jie, Lebœuf, David, Frontier, Alison J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104681/
https://ncbi.nlm.nih.gov/pubmed/21466152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111504w
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