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Constraining local structure can speed up folding by promoting structural polarization of the folding pathway
The pathway which proteins take to fold can be influenced from the earliest events of structure formation. In this light, it was both predicted and confirmed that increasing the stiffness of a beta hairpin turn decreased the size of the transition state ensemble (TSE), while increasing the folding r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104226/ https://ncbi.nlm.nih.gov/pubmed/21413096 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.619 |
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