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Human and human-yeast chimeric U6 snRNA genes identify structural elements required for expression in yeast.

U6 is the most highly conserved spliceosomal snRNA. Previous mutational studies have shown that the majority of essential residues in U6 are located in a region of 35 nucleotides encompassing a conserved hexanucleotide and stem I and stem II of the U4-interaction domain. Although the yeast and human...

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Autors principals: Bordonné, R, Guthrie, C
Format: Artigo
Idioma:Inglês
Publicat: 1992
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC310411/
https://ncbi.nlm.nih.gov/pubmed/1741282
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