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Imaging and nanodissection of individual supercoiled plasmids by atomic force microscopy.
The atomic force microscope (AFM) was used to image supercoiled plasmid DNA deposited on a mica surface in either a hydrated or desiccated state. Hydrated plasmid was precisely cut by the scanning tip at a location determined by the instrument operator. Small pieces of DNA (100-150 nm in length) wer...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1992
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC310406/ https://ncbi.nlm.nih.gov/pubmed/1741278 |
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