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Chiral Calcium VAPOL Phosphate Mediated Asymmetric Chlorination and Michael Reactions of 3-Substituted Oxindoles

We disclose a novel high yielding and highly enantioselective chiral calcium VAPOL phosphate-catalyzed chlorination of 3-substituted oxindoles with N-chlorosuccinimide (NCS). The reaction conditions are also shown to be effective for the catalytic enantioselective Michael addition of 3-aryloxindoles...

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Hlavní autoři: Zheng, Wenhua, Zhang, Zuhui, Kaplan, Matthew J., Antilla, Jon C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103939/
https://ncbi.nlm.nih.gov/pubmed/21341790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja109824x
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