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Mitochondria-Targeted Peptide Accelerates ATP Recovery and Reduces Ischemic Kidney Injury

The burst of reactive oxygen species (ROS) during reperfusion of ischemic tissues can trigger the opening of the mitochondrial permeability transition (MPT) pore, resulting in mitochondrial depolarization, decreased ATP synthesis, and increased ROS production. Rapid recovery of ATP upon reperfusion...

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Detalhes bibliográficos
Main Authors: Szeto, Hazel H., Liu, Shaoyi, Soong, Yi, Wu, Dunli, Darrah, Shaun F., Cheng, Feng-Ying, Zhao, Zhihong, Ganger, Michael, Tow, Clara Y., Seshan, Surya V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103724/
https://ncbi.nlm.nih.gov/pubmed/21546574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010080808
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