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The intracellular sensor Nod2 Promotes Intestinal Pathogen Eradication via the chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes
The intracellular sensor Nod2 is activated in response to bacteria, and the impairment of this response is linked to Crohn’s disease. However, the function of Nod2 in host defense remains poorly understood. We found that Nod2(−/−) mice exhibited impaired intestinal clearance of Citrobacter rodentium...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3103637/ https://ncbi.nlm.nih.gov/pubmed/21565531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.04.013 |
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