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The human insulin gene linked polymorphic region exhibits an altered DNA structure.

Regulation of transcription of the human insulin gene appears to involve a series of DNA sequences in the 5' region. Hypersensitivity to DNA structural probes has previously been demonstrated in regulatory regions of cloned genomic DNA fragments, and been correlated with gene activity. To inves...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Hammond-Kosack, M C, Dobrinski, B, Lurz, R, Docherty, K, Kilpatrick, M W
Format: Artigo
Language:Inglês
Published: Oxford University Press 1992
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310359/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741248/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.2.231
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