IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

Chronic Obstructive Pulmonary Disease (COPD) is characterized by airspace enlargement and peribronchial lymphoid follicles; however, the immunological mechanisms leading to these pathologic changes remain undefined. Here we show that cigarette smoke is a selective adjuvant that augments in vitro and...

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Main Authors: Chen, Kong, Pociask, Derek A., McAleer, Jeremy P., Chan, Yvonne R., Alcorn, John F., Kreindler, James L., Keyser, Matthew R., Shapiro, Steven D., Houghton, A. McGarry, Kolls, Jay K., Zheng, Mingquan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103542/
https://ncbi.nlm.nih.gov/pubmed/21647421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020333
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