HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway

Diminished adult neurogenesis is considered a potential mechanism in the pathogenesis of HIV-1-associated dementia (HAD). In HAD, HIV-1-infected and immune-activated brain mononuclear phagocytes (MP; perivascular macrophages and microglia) drive central nervous system (CNS) inflammation and may alte...

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Bibliografiske detaljer
Main Authors: Peng, Hui, Sun, Lijun, Jia, Beibei, Lan, Xiqian, Zhu, Bing, Wu, Yumei, Zheng, Jialin
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103496/
https://ncbi.nlm.nih.gov/pubmed/21637744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019439
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