HIV-1-Infected and Immune-Activated Macrophages Induce Astrocytic Differentiation of Human Cortical Neural Progenitor Cells via the STAT3 Pathway

Diminished adult neurogenesis is considered a potential mechanism in the pathogenesis of HIV-1-associated dementia (HAD). In HAD, HIV-1-infected and immune-activated brain mononuclear phagocytes (MP; perivascular macrophages and microglia) drive central nervous system (CNS) inflammation and may alte...

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Bibliografische gegevens
Hoofdauteurs: Peng, Hui, Sun, Lijun, Jia, Beibei, Lan, Xiqian, Zhu, Bing, Wu, Yumei, Zheng, Jialin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3103496/
https://ncbi.nlm.nih.gov/pubmed/21637744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019439
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